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Archive Number 20100205.0393
Published Date 05-FEB-2010
Subject PRO/AH/EDR> Influenza pandemic (H1N1), animal (05): turkeys, insemination

INFLUENZA PANDEMIC (H1N1), ANIMAL (05): TURKEYS, INSEMINATION
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A ProMED-mail post
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Date: Wed 3 Feb 2010
Source: Virology Journal [edited]
<http://www.virologyj.com/content/pdf/1743-422x-7-27.pdf>


[Ref: Pantin-Jackwood M, Wasilenko JL, Spackman E, et al:  
Susceptibility of turkeys to pandemic-H1N1 virus by reproductive tract  
insemination. Virol J. 2010 Feb 3; 7(1): 27. Epub ahead of print]
----------------------------------------------------------------------
[A provisional PDF, which corresponds to the peer-reviewed article as  
it appeared upon acceptance. Fully formatted PDF and full text (HTML)  
versions will be made available soon by Virology Journal.]

Abstract
--------
The current pandemic influenza A H1N1 2009 (pH1N1) was first  
recognized in humans with acute respiratory diseases in April 2009 in  
Mexico, in swine in Canada in June 2009 with respiratory disease, and  
in turkeys in Chile in June 2009 with a severe drop in egg production  
[see ProMED 2009 refs. below]. Several experimental studies attempted  
to reproduce the disease in turkeys, but failed to produce respiratory  
infection in turkeys using standard inoculation routes. We  
demonstrated that pH1N1 virus can infect the reproductive tract of  
turkey hens after experimental intrauterine inoculation, causing  
decreased egg production. This route of exposure is realistic in  
modern turkey production because turkey hens are handled once a week  
for intrauterine insemination in order to produce fertile eggs. This  
understanding of virus exposure provides an improved understanding of  
the pathogenesis of the disease and can improve poultry husbandry to  
prevent disease outbreaks.

--
Communicated by:
ProMED-mail
<promed@promedmail.org>

[H1N1 has been, so far, officially reported from turkey farms in 4  
countries: Chile (July 2009), Canada (October 2009), USA (Virginia,  
November 2009; California, December 2009), and France (Jan 2010) --  
see ProMED rafs. below. All those events related to breeding flocks  
where artificial insemination is practiced. It appears that  
intracloacal and intrauterine routes are the only way to infect  
turkeys with the influenza pandemic (H1N1) virus. The finding of the  
authors above, at the Exotic and Emerging Avian Viral Diseases  
Research Unit, Agricultural Research Service, US Department of  
Agriculture, Athens, Georgia is unambiguous and leads to practical,  
applicable consequences to prevent such infections.

Note that "swine influenza" (hog flu, pig flu) sensu stricto, an  
animal disease caused by a specific porcine virus, namely swine  
influenza virus (SIV; not H1N1), is known to sporadically cause  
disease in turkeys (and humans). When it occurs, it is not followed by  
further spread in the affected populations ("dead end" hosts). - Mod.AS]

[see also:
Influenza pandemic (H1N1), animal (04): global, update 20100131.0337
Influenza pandemic (H1N1), animal (02): USA, turkey 20100108.0087
2009
----
Influenza pandemic (H1N1) 2009, animal health (14): Canada (ON), avian  
20091020.3602
Influenza pandemic (H1N1) 2009, animal health (04): Chile, avian, OIE  
20090823.2978
Influenza A (H1N1): animal health (13) swine, Canada, origin, RFI  
20090615.2215]
........................................arn/mj/jw
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